CLC is a 38-year-old female two-month post kidney transplant for Immunoglobulin A (‘IgA’) nephropathy related kidney failure. Her transplant rejection prophylaxis regimen include oral tacrolimus, mycophenolate mofetil and prednisolone.
(a) Please advise on any necessary screening and monitoring parameters for CLC’s anti-rejection medications. (5 marks)
(b) Describe the antimicrobial prophylaxis that should be given to CLC at this moment. (5 marks)
(c) CLC is confirmed to have candida albicans oesophagitis requiring systemic antifungal treatment. Please explain which antifungal agent you would recommend. (5 marks)