1A) Define the terms ‘bactericidal’ and ‘bacteriostatic’ used to classify antibiotics with examples. (8 marks)

1B) A 70 year old man is going to have his remaining teeth extracted for subsequent dentures. He has mitral valve stenosis. The dentist decides that his medical history warrants prophylactic antibiotic therapy prior to the procedure. Give the name of the antibiotics the man is likely to have been given. What is the mechanism of action of this antibiotic? List at least two common adverse effects. (3 marks)

1C) Briefly explain the mechanism of action and mechanism of resistance of aminoglycosides (eg. Gentamicin) (6 marks)

1D) List at least three factors than can increase the prevalence of antibiotic resistance over the years. (3 marks)