Question
Mrs Lee is a 47-year-old married clerk. There was a reduction of manpower in her department in the company 3 months ago and she felt increasingly stressed at work. Her concentration has gotten worse and she found it more difficult to get things done. Her mood is low almost every day and has been tearful for no reason. She becomes tired easily and her sleeping pattern is altered (insomnia). She also loses her appetite and has lost 5 kilograms in the recent two months.
(a) What type of disorder does Mrs Lee likely have? Explain your answer. Name TWO addition symptoms of this disorder. (2+2 marks)
(b) Describe "monoamine hypothesis". Explain whether this hypothesis is perfect or not. (4 marks)
(c) What is the drug class and mode of action of Fluoxetine? (2 marks)
(d) Explain the mode of action of serotonin antagonist-reuptake inhibitor Trazodone in treating depression and name TWO side effects. (4+2 marks)
(e) Explain why monoamine oxidase inhibitor ("MAOI") should not be taken together with banana or cheese. (4 marks)